%PDF-1.4
%
1 0 obj
<<
/Names 2 0 R
/Outlines 3 0 R
/Metadata 4 0 R
/Pages 5 0 R
/Type /Catalog
/PageLabels 6 0 R
>>
endobj
7 0 obj
<<
/CreationDate (D:20230222101811+05'30')
/Creator (Arbortext Advanced Print Publisher 9.1.510/W Unicode)
/Producer (Acrobat Distiller 7.0 \(Windows\))
/ModDate (D:20230222101811+05'30')
>>
endobj
2 0 obj
<<
/Dests 8 0 R
>>
endobj
3 0 obj
<<
/First 9 0 R
/Count 1
/Last 9 0 R
>>
endobj
4 0 obj
<<
/Type /Metadata
/Subtype /XML
/Length 10 0 R
>>
stream
dvips + MiKTeX GPL Ghostscript 9.0
actively spreading material, site preservation, cell spheroid, polyether F127 diacrylate, mesenchymal stem cell
A three-dimensional actively spreading bone repair material based on cell spheroids can facilitate the preservation of tooth extraction sockets
Xinwei Guo
Huimin Zheng
Yusi Guo
Boon Chin Heng
Yue Yang
Weitong Yao
Shengjie Jiang
Introduction: Achieving a successful reconstruction of alveolar bone morphology still remains a challenge because of the irregularity and complex microenvironment of tooth sockets.
actively spreading materialsite preservationcell spheroidpolyether F127 diacrylatemesenchymal stem cell
false
false
endstream
endobj
5 0 obj
<<
/Count 9
/Type /Pages
/Kids [11 0 R 12 0 R 13 0 R 14 0 R 15 0 R 16 0 R 17 0 R 18 0 R 19 0 R]
>>
endobj
6 0 obj
<<
/Nums [0 20 0 R]
>>
endobj
8 0 obj
<<
/Kids [21 0 R 22 0 R]
>>
endobj
9 0 obj
<<
/First 23 0 R
/Parent 3 0 R
/Dest
/Count -12
/Last 24 0 R
/Title
>>
endobj
10 0 obj
3028
endobj
11 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [25 0 R 26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R
35 0 R 36 0 R 37 0 R 38 0 R 39 0 R 40 0 R 41 0 R]
/Parent 5 0 R
/Contents [42 0 R 43 0 R 44 0 R 45 0 R 46 0 R 47 0 R 48 0 R 49 0 R]
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 50 0 R
/Resources 51 0 R
/Type /Page
>>
endobj
12 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [52 0 R 53 0 R 54 0 R 55 0 R 56 0 R 57 0 R 58 0 R 59 0 R 60 0 R 61 0 R
62 0 R 63 0 R 64 0 R 65 0 R 66 0 R 67 0 R 68 0 R 69 0 R 70 0 R 71 0 R
72 0 R 73 0 R 74 0 R 75 0 R 76 0 R 77 0 R 78 0 R]
/Parent 5 0 R
/Contents 79 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 80 0 R
/Resources 81 0 R
/Type /Page
>>
endobj
13 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [82 0 R 83 0 R 84 0 R 85 0 R]
/Parent 5 0 R
/Contents 86 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 87 0 R
/Resources 88 0 R
/Type /Page
>>
endobj
14 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [89 0 R 90 0 R 91 0 R 92 0 R 93 0 R 94 0 R 95 0 R 96 0 R 97 0 R]
/Parent 5 0 R
/Contents 98 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 99 0 R
/Resources 100 0 R
/Type /Page
>>
endobj
15 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [101 0 R 102 0 R 103 0 R 104 0 R 105 0 R 106 0 R]
/Parent 5 0 R
/Contents 107 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 108 0 R
/Resources 109 0 R
/Type /Page
>>
endobj
16 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [110 0 R 111 0 R 112 0 R 113 0 R 114 0 R 115 0 R 116 0 R 117 0 R 118 0 R 119 0 R
120 0 R 121 0 R 122 0 R]
/Parent 5 0 R
/Contents 123 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 124 0 R
/Resources 125 0 R
/Type /Page
>>
endobj
17 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [126 0 R 127 0 R 128 0 R 129 0 R 130 0 R 131 0 R]
/Parent 5 0 R
/Contents 132 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 133 0 R
/Resources 134 0 R
/Type /Page
>>
endobj
18 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [135 0 R 136 0 R 137 0 R 138 0 R 139 0 R 140 0 R 141 0 R 142 0 R 143 0 R 144 0 R
145 0 R 146 0 R 147 0 R 148 0 R 149 0 R 150 0 R]
/Parent 5 0 R
/Contents 151 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 152 0 R
/Resources 153 0 R
/Type /Page
>>
endobj
19 0 obj
<<
/CropBox [0 0 595.2760009766 841.8900146484]
/Annots [154 0 R 155 0 R 156 0 R 157 0 R 158 0 R 159 0 R 160 0 R 161 0 R 162 0 R 163 0 R
164 0 R 165 0 R 166 0 R 167 0 R 168 0 R 169 0 R 170 0 R 171 0 R 172 0 R 173 0 R
174 0 R 175 0 R 176 0 R 177 0 R 178 0 R 179 0 R 180 0 R 181 0 R 182 0 R 183 0 R
184 0 R 185 0 R 186 0 R 187 0 R 188 0 R 189 0 R 190 0 R 191 0 R 192 0 R 193 0 R
194 0 R 195 0 R 196 0 R 197 0 R 198 0 R]
/Parent 5 0 R
/Contents 199 0 R
/Rotate 0
/MediaBox [0 0 595.2760009766 841.8900146484]
/Thumb 200 0 R
/Resources 201 0 R
/Type /Page
>>
endobj
20 0 obj
<<
/S /D
>>
endobj
21 0 obj
<<
/Limits [ ]
/Names [ 202 0 R 203 0 R 204 0 R 205 0 R 206 0 R
207 0 R 208 0 R 209 0 R 210 0 R 211 0 R
212 0 R 213 0 R 214 0 R 215 0 R 216 0 R
217 0 R 218 0 R 219 0 R 220 0 R 221 0 R
222 0 R 223 0 R 224 0 R 225 0 R 226 0 R
227 0 R 228 0 R 229 0 R 230 0 R 231 0 R
232 0 R 233 0 R 234 0 R 235 0 R 236 0 R
237 0 R 238 0 R 239 0 R 240 0 R 241 0 R
242 0 R 243 0 R 244 0 R 245 0 R 246 0 R
247 0 R 248 0 R 249 0 R 250 0 R 251 0 R
252 0 R 253 0 R 254 0 R 255 0 R 256 0 R
257 0 R 258 0 R 259 0 R 260 0 R 261 0 R
262 0 R 263 0 R 264 0 R 265 0 R]
>>
endobj
22 0 obj
<<
/Limits [ ]
/Names [ 266 0 R 267 0 R 268 0 R 269 0 R 270 0 R
271 0 R 272 0 R 273 0 R 274 0 R 275 0 R
276 0 R 277 0 R 278 0 R 279 0 R 280 0 R
281 0 R 282 0 R 283 0 R 284 0 R 285 0 R
286 0 R 287 0 R 288 0 R]
>>
endobj
23 0 obj
<<
/Parent 9 0 R
/Next 289 0 R
/Dest
/Title
>>
endobj
24 0 obj
<<
/Parent 9 0 R
/Dest
/Prev 290 0 R
/Title
>>
endobj
25 0 obj
<<
/Rect [219.6849975586 688.3649902344 495.949005127 709.2849731445]
/Subtype /Link
/A 291 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
26 0 obj
<<
/Rect [219.6849975586 663.4199829102 517.3229980469 684.3400268555]
/Subtype /Link
/A 292 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
27 0 obj
<<
/Rect [219.6849975586 638.5319824219 490.9609985352 659.4520263672]
/Subtype /Link
/A 293 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
28 0 obj
<<
/Rect [219.6849975586 613.6439819336 545.6690063477 634.5640258789]
/Subtype /Link
/A 294 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
29 0 obj
<<
/Rect [219.6849975586 588.6989746094 396.4530029297 609.674987793]
/Subtype /Link
/A 295 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
30 0 obj
<<
/Rect [49.6059989929 694.2050170898 121.5500030518 708.3779907227]
/Subtype /Link
/A 296 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
31 0 obj
<<
/Rect [49.6059989929 552.6420288086 53.9720001221 556.3270263672]
/Subtype /Link
/A 297 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
32 0 obj
<<
/Rect [56.0130004883 550.9979858398 149.3860015869 557.9719848633]
/Subtype /Link
/A 298 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
33 0 obj
<<
/Rect [63.9500007629 349.7390136719 152.3339996338 356.7120056152]
/Subtype /Link
/A 299 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
34 0 obj
<<
/Rect [49.6059989929 299.4519958496 173.2530059814 306.424987793]
/Subtype /Link
/A 300 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
35 0 obj
<<
/Rect [49.6059989929 290.4379882812 74.2679977417 297.4110107422]
/Subtype /Link
/A 301 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
36 0 obj
<<
/Rect [49.6059989929 33.6759986877 200.2389984131 40.6489982605]
/Subtype /Link
/A 302 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
37 0 obj
<<
/Rect [499.9750061035 33.6759986877 545.6690063477 40.6489982605]
/Subtype /Link
/A 303 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
38 0 obj
<<
/Rect [49.6059989929 787.9180297852 325.4169921875 801.9210205078]
/Subtype /Link
/A 304 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
39 0 obj
<<
/Rect [444.8689880371 800.049987793 457.8519897461 805.5490112305]
/Subtype /Link
/A 305 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
40 0 obj
<<
/Rect [457.8519897461 799.7100219727 516.2459716797 806.6829833984]
/Subtype /Link
/A 306 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
41 0 obj
<<
/Rect [457.2850036621 781.7379760742 545.6690063477 788.7119750977]
/Subtype /Link
/A 307 0 R
/Border [0 0 0]
/Type /Annot
>>
endobj
42 0 obj
<<
/Length 308 0 R
/Filter /FlateDecode
>>
stream
HWr8}WFē*lֳ4[Pۚ hIiU2Hӧo>^p˛g"<
E%3mjq9y~yVr~t'ⲡ+t)%4˕np[ l;X7UMnˮI6d3y5`ߦE 7[JRM;)"u@8uY%K>]",v昼%PT Br}BFb5Vւ+8e&*/ Jd42N*|
֍>h=_DN0[ʗZd*ɞu您ٙO`$/>: N0*281G<^>2^'#`EX彬 jSzyU4ə0gr
xu([T%joP$V_spvb`ӜLHoHq}+ؗYn9A?QN4w]3/?47.,/WDBLHU.Z PR>[T 4:8%y .F[[_v`%{}|4Y@JI٫JB{:ܐ 4tGh~_d~e3E
%UA\?
gΡ`VG[2ESE8XQ*Ƅy =-49Ŀ
9{E`#
Bskޣ/_F_E2(4]S\Fypu<_~{1ߧu=c% ^X4[S_,bsDJ
F.WQq̹s]%?nwl{"2/4.LR-c?X_t1uqZ2./%.ǫ=)ԁ0uDpEMb惊.sΒ4uu<ޛ}ޯM|TAB6)%+*$ֽ<|[ lm6]P璹pBm7 Heym Gy/v\TЫD'._~0mmo1gxёZYRn:
YƑa
'DQ2k ˬ
/\]>q'h\&dRlvlR>)DJ\6f%U@[KW_Hr6lw!Zho@Y6 KJc?Wm;LԉSW+[!m
ET Y Cv8n3ܒZDFw1UQRBU8۸:6)TTENj<'pnUEo{OZj~~E{m0@c/
&!t&gh,BQ2ЋJkQgRέ&@/ /BvEC9vU 'Ĥ%%e%E*ꇸf(vA@(ԺTA=DctvQPޜ$<&G_uMFty=Bx@o+%h0Mң++\3hW3赜SkS|Rsڵh
o˄5y:Xfq2gwΧ)ii} *+5QhHIp.yGLwI@
:."c~ E:ejI8y7.>A`hE'oú҃P
G]_אP4AIx)#`ux,O
puwh-CxVO=?L(Nt:."ؗ1x w}bi5" QȮBZd@c\/< zAY͛9b]g?/CB&z̩Z|OCj+llU-|ň틕I7 g\|qsL26A5Pz2lUK. FF穓vx
vɲ+?/`w)(O9ODU+eDPL)-^VKSTi9=N?rBTwNͶ&2HO#>pVJ{j-X.Sұqt7YGrHf/
ӫ*^cuUUY+ּJj.(
DTU84O:qB]ܘ.xO6 ~tYuO*"f(^QL5~H8^cJM^?m,=iRLhٓx_x$PGLM=[kdAFE|w*ci5=֦~
nni%1F]L=00ȅ/%O*i0X(hfjk37l!9XR\|-;F6 sbȕDЎ(SdrM@x,4XY5"GM#݀ϲ)Er"̘xNf1]zv?z:AdT{;~Pko`uaok[-G-#")z,elBYL]vw!XCTB}CJ*hT U%BZg?\2;W7Gӏϯ/pk7Y%
v0W
mXV\ -
endstream
endobj
43 0 obj
<<
/Length 309 0 R
/Filter /FlateDecode
>>
stream
HWˮe9
?y8BHH j@KQ[-A
}啜st.;qXvDn6yT
^G/h^ڎ0| hx0˸Kgl~_zWw5mu\5ݭ_ۊ:/_|\_?_!?0`qNysonzy_\?~w%tw\ן\5p/:s-a0蕃}uo߭_~9B ƺsG]%uLl+*a#ZpKVtq@& ӓ ˭DiB^_װ{l
hpzֹRb (ԴR{3aI4muq5 (P!b)v\rO?{[P[8`^a$#uy]kmP.nr&mQ&mAF=Ю4u-V&$u j:-/jn=Ib[Jng3<kx%ltIX+XyrBOMz{BklaF >_Qn>vRJ.6sbS}x0L udȣ*K![^%s,s1^F d5x@+V/: `'v
hÐn=Yax۔'`9i&ZZ:j8ܣ
"),gL?!!Αpӷ[|?ilЭ.zOB
z98p9o-yZNU"#I\`+?
KryF9Ҕz"fn
_k?BP
Kj.2]/(6<#Mldw^AK.Y)rZӍyNxM\[:}xb%BĘ0aF=+{͞b~qW"IJt\7Qsw nC+`U%
6aZ\*Qdnӫ## ZwfF cU
.Kw"OFGsR; a9TaZ2TMutUH'#SB&v#P _#6RNy|Ɩż
Ğ<q2Y^T@NgSv:T-{OD){+\HA:!TW{wǂ_=}o$$ez}
cO^#fm"eL
P,m#)mL
W]m1GYOv~!4Y6+H#SGj/vc1X6otIW]=nQ(M?YvANY-;>fF)A%r,1^5SmB
(]Za%ErNAq2w)e ǩjhW
zvmFgž}[A+N-_ hv\Z["_|T¦6\6>lcADg$wڽei5Z騤v5K\(FKTL۽9ˎ́zNkٙ7CzHE?͇OY(Y/>wN?ooJL"&O@#fiZ|D^Isqhw
^+M6PGS6ymʇ\*%<]#U**NqW>LchU>èq30h<(IffERn,1?OZ֨I6yS}zJًyQ!U͂5'7gL)O(4Wv'd$;m;Ѕ|}#st>x=D*rRVVY'ĸ{r >_:3:Es*o)7!Ζ(_c#4jӓأY(/zlE}
s>{/UA?:!PO#[D7# >81z97Hu}*
rzhyUv`4RTA
&o]ˇʂF76GlN˳&+mWTG!q4`gԖ}iK횗-OBbXgK? @R A|LRvs[{4-U!ѪWa7.(5m(fʀ 9='3Yx>Q8bz%q
q4 vMX-Ppe%+knQ>T^a#뤺p9R+ BӐrT7U5rMUAlWaceƅpyVw@5J2Va̐.78N0x33̸z
93 33;z㣱Z[DZJ.//ijc\vӬVq⤺k`eiRIA_P_!#AQ]ּ>3Ylnž}]nT$=_b"GΓv_/CxbaC
W?#:$Qr3axP}DQ/Q.t/*(pz)s.u-UN
`Yyًg;:pt{P?6iPGpH'IPk!2
wᨈ3dQG*?/H}tWLW#PuГ0ˠr7*br?O
endstream
endobj
44 0 obj
<<
/Length 310 0 R
/Filter /FlateDecode
>>
stream
HtWK$+)i