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T*
[(stu)14(dy)-313.2(was)-310.4(app)12.8(rov)14(ed)-314.4(by)-313.2(the)-309.9(eth)12.7(ics)-309.7(com)17.4(mit)12.5(tee)-311(at)-314.5(Pek)13(ing)-308.7(Uni)13(-)]TJ
0 -1.1174 TD
[(ver)12.8(sit)13.9(y)-456.1(Sch)13(ool)-452.7(an)13.9(d)-461.9(Hos)13.3(pit)13.7(al)-452.7(of)-451.4(Sto)14(mat)11.5(olo)13.8(gy)-451.5(\(PK)13.3(USS)13.4(IRB)11.9(-)]TJ
0 -1.1116 TD
[(202)14(054)14(054)14(\))-433(and)-430.7(all)-425.2(pat)12.7(ien)12.7(ts)-428.4(wer)12(e)-440(req)12.8(ui)15(red)-430.6(to)-434.3(sig)19.8(n)-438.8(wri)13(tte)12.6(n)]TJ
T*
[(inf)13.9(orm)12.8(ed)-412.3(con)12.8(sen)18.8(t.)-413.6(Rad)11.8(iog)13.8(rap)12.8(hic)-407.8(exa)17.4(min)12.6(ati)12.6(on)-411.1(and)-407.6(tho)13.9(rou)14(gh)]TJ
0 -1.1174 TD
[(vis)14(ual)-327.1(ins)14(pec)11.7(tio)13.7(n)-340.9(usi)19.8(ng)-336.3(a)-336.3(den)12.8(tal)-333(mi)13.7(rro)14(r)-340.9(and)-327(pro)14(be)-337.4(we)13(re)-337.4(per)12.8(-)]TJ
0 -1.1116 TD
[(for)14(med)11.6(.)-383.6(For)-371.7(inc)12.7(lus)14(ion)-372.1(in)-376.7(the)-379(stu)19.8(dy,)-374.3(the)-379(sub)19.9(jec)11.5(ts)-382.3(sho)14.2(uld)-372(not)]TJ
T*
[(hav)12.8(e)-319(und)14(erg)12.8(one)-309.7(per)12.8(iod)19.6(ont)13.8(al)-314.5(sca)11.8(lin)13.7(g)-317.9(i)0(n)-319.1(t)0(h)15(e)-324.8(pa)13.9(st)-318.9(2)-317.9(wee)10.8(ks)-313(and)]TJ
0 -1.1174 TD
[(per)12.8(iod)13.9(ont)13.8(al)-251.2(sur)14.2(ge)13.9(ry)-255.6(in)-250(th)15(e)-255.7(pas)13(t)-254.7(3)-260.3(mo)13.8(nth)13.9(s)-254.3(and)-246.4(sho)14.2(uld)-245.3(not)-245.3(hav)12.8(e)]TJ
0 -1.1116 TD
[(tak)12.7(en)-377.7(any)-378.8(med)17.3(ica)11.5(tio)13.7(n)-387(\(in)13.9(cl)13.8(udi)13.8(ng)-382.3(ant)12.7(i-i)13.8(na)18.7(mma)10.4(tor)13.9(y)-381.2(and)-378.8(an-)]TJ
T*
[(alg)12.7(esi)12.9(c\))-176.1(or)-180.7(rec)11.7(eiv)12.7(ed)-176.2(pro)14(fes)13(sio)14(nal)-177.4(des)13(ens)13(iti)19.4(zat)11.5(ion)-176.2(the)12.7(rap)12.9(y)-179.6(i)0(n)-180.9(the)]TJ
T*
[(pre)12.8(vio)13.9(us)-399.4(6)-410(m)0(o)13.8(nth)13.8(s.)-401.8(The)-397.3(tee)11.5(th)-399.7(sho)14.2(win)13(g)-410(sen)18.8(sit)13.9(ivi)13.7(ty)-405.5(we)13(re)-406.5(re-)]TJ
0 -1.1174 TD
[(qui)13.8(red)-407.6(to)-417(be)-412.3(wit)12.8(hou)14(t)-415.9(def)12.8(ect)11.5(ive)-407.8(res)13(tor)13.9(ati)12.6(ons)14.2(,)-418.1(c)0(a)12.8(rie)12.7(s,)-413.3(ll)13.9(ing)13.8(s,)]TJ
0 -1.1116 TD
[(cra)11.7(cks)13(,)-331.7(a)0(n)13.9(d)-335.2(pul)13.8(pi)14.9(tis)13.9(.)-331.7(Pat)12.8(ien)12.7(ts)-324.7(wit)12.8(h)-329.4(poo)14(r)-335.1(o)0(r)15.1(a)0(l)-331.8(hyg)19.7(ien)12.7(e,)-328.2(sev)13(ere)]TJ
T*
[(per)12.8(iod)13.9(ont)13.8(iti)13.6(s,)-211.7(and)-211.8(the)-206.2(tee)11.5(th)-215.4(wit)12.8(h)-214.2(wed)11.9(ge-)12.8(sha)13(ped)-211.8(de)13.9(fec)11.7(ts)-215.2(dee)11.7(per)]TJ
0 -1.1174 TD
[(tha)12.7(n)-335.2(1)-162.4(mm)-333(wer)12(e)-336.3(als)12.9(o)-335.2(exc)11.7(lu)15(ded)12.8(.)-337.5(Las)11.8(t,)-327.2(pre)12.9(gna)12.8(nt)-330.6(and)-327(lac)11.5(tat)12.6(ing)]TJ
0 -1.1116 TD
[(wom)11.9(en)-337.4(\(to)-331.7(avo)12.8(id)-336.4(the)-332.9(pro)14(bab)12.8(le)-337.6(sid)14(e)-342.1(eff)12.9(ec)12.8(ts)-342(of)-336.2(the)-332.9(las)12.9(er\))-332.7(and)]TJ
T*
[(tho)13.8(se)-504.3(wit)12.8(h)-507.9(sys)14.4(tem)11.5(ic)-504.6(dis)14(ea)12.8(ses)-499.4(or)-509(al)13.8(ler)12.7(gie)12.7(s)-507.8(t)0(o)-503.4(des)13(ens)13(iti)13.6(zin)12.7(g)]TJ
0 -1.1174 TD
[(age)11.7(nts)-262.4(wer)12(e)-278.7(als)12.9(o)-271.8(exc)11.7(lud)13.9(ed.)]TJ
1.0137 -1.1116 TD
[(We)-218.7(enrolled)-224.5(48)-215.3(participants)-224.4(\(15)-216.4(male)-221.2(and)-223.3(33)-215.3(female;)-225.8(mean)]TJ
-1.0137 -1.1116 TD
[(age,)-452.6(43.6)-450.2(years;)-452.3(age)-454.9(range,)-449(2372)-449(years\))-457.9(with)-449(96)-451.5(dentin-)]TJ
25.504 67.9242 TD
[(exposed)-274.8(teeth)-278.8(\(40)-268.2(teeth)-273(on)-272.9(the)-275.3(facial)-275.3(surface)-275.9(and)-269.4(56)-272.9(teeth)-273(on)]TJ
0 -1.1174 TD
[(the)-367.5(occlusal)-363.7(surface\))-363.4(in)-365.2(this)-361.6(randomized)-367.2(controlled)-359.3(clinical)]TJ
0 -1.1116 TD
[(trial.)-189(Subjects)-183.8(were)-180.4(instructed)-186.3(to)-180.9(refrain)-188.6(from)-178.4(carrying)-189.8(out)-182(any)]TJ
T*
[(oral)-299.4(hygiene)-298.2(measures,)-304.5(eating,)-294.9(or)-295.9(drinking)-297(water)-302.5(at)-297.2(least)-295.9(2)-168.1(h)]TJ
T*
[(before)-538.8(the)-528.7(evaluation.)-536.7(Detailed)-531.9(anam)-8(nesis)-530.5(interviews)-532.8(in-)]TJ
0 -1.1174 TD
[(cluding)-423.8(diet,)-412.4(chewing)-420(habits)-422.5(and)-413.4(time,)-419.4(and)-419.2(frequency)-422.3(and)]TJ
0 -1.1116 TD
[(degree)-390.2(of)-382.3(hypersensitivity)-388.8(were)-387.7(recorded)-386.6(before)-383.3(treatment.)]TJ
T*
[(Clinical)-467.7(examinations)-467.4(were)-462.6(performed)-468.4(including)-460.7(oral)-466.4(soft)]TJ
0 -1.1174 TD
[(tissue)-347.5(including)-339.8(soft)-344.1(tissue)-341.7(in)-342.1(oral)-339.7(and)-344.3(the)-338.7(wear)-341.6(position)-343.1(of)]TJ
0 -1.1116 TD
[(sensitive)-277.2(tooth.)-268.4(The)-270.6(vitality)-269.8(of)-272.9(all)-269.7(experimental)-272.9(and)-275.2(adjacent)]TJ
T*
[(teeth)-440.1(was)-442.9(checked)-438.6(through)-439.8(an)-441.1(electric)-440(pulp)-436.5(tester)-440.9(and)-436.4(re-)]TJ
0 -1.1174 TD
[(corded.)-248.5(Each)-249.8(sensitive)-248.4(tooth)-247.7(was)-247.1(examined)-249.8(in)-244.2(two)-246.2(ways)-248.2(cold)]TJ
0 -1.1116 TD
[(test)-368.5(and)-361.6(probing)-364.9(test.)-360.4(Cotton)-365(rolls)-362.6(and)-361.6(suction)-366(device)-367.3(were)]TJ
T*
[(applied)-269.5(to)-267.3(isolate)-269.4(the)-269.5(adjacent)-272.9(teeth.)-270.7(An)-262.3(ice)-270.7(stick)-265.9(was)-270.1(placed)]TJ
T*
[(on)-330.5(the)-332.9(tooth)-334.1(being)-329.3(tested)-331.5(for)-331.5(5)-168.1(sec,)-331.4(and)-332.8(all)-333(the)-332.9(stimuli)-331.8(were)]TJ
0 -1.1174 TD
[(applied)-211.9(on)-203.8(the)-206.2(sensitive)-208.1(region)-203.7(of)-209.5(the)-200.4(experimental)-215.3(tooth.)-205(The)]TJ
0 -1.1116 TD
[(patients)-420.3(were)-422.3(asked)-416.6(to)-417(describe)-421.1(the)-419.3(pain)-414.6(intensity)-420.3(ranging)]TJ
T*
[(from)-397.2(0)-392.8(t)0(o)-394(1)0(0)-393.9(according)-399.4(to)-394(a)-393.9(visual)-393.7(analogue)-398.3(scale)-394.8(\(VAS\).)]TJ
0 -1.1174 TD
[(These)-371.7(scores)-371.4(were)-370.4(recorded)-375.1(as)-366(the)-373.2(baseline)-369.5(VAS)-367.7(score)-370.5(for)]TJ
0 -1.1116 TD
[(each)-359.2(experimental)-353.5(tooth)-351.4(or)-353.5(sensitive)-357.8(point.)-349(Scores)]TJ
/F8 1 Tf
20.9423 0 TD
(>)Tj
/F6 1 Tf
.5529 0 TD
[(2)-352.4(were)]TJ
-21.4952 -1.1116 TD
[(included)-316.7(to)-313.3(standardize)-316.3(the)-309.9(sample.)-313(After)-312.9(5)-168.1(min,)-313.4(the)-309.9(experi-)]TJ
0 -1.1174 TD
[(mental)-269.6(teeth)-261.5(were)-266.8(touched)-263.6(by)-261.4(an)-262.6(explorer)-270.4(with)-259(a)-267.2(force)-261.2(of)-261.4(5)-168.1(g)]TJ
0 -1.1116 TD
[(and)-286.7(the)-281.1(VAS)-281.4(was)-281.6(again)-278.7(recorded.)]TJ
1.0137 -1.1116 TD
[(After)-566.3(recording)-565.2(the)-563.3(baseline)-565.3(VAS)-563.6(scores,)-564.9(participants)]TJ
-1.0137 -1.1174 TD
[(were)-341.6(randomly)-333.8(assigned)-333.4(to)-336.4(three)-336.2(groups:)]TJ
1.6703 -2.2232 TD
[(I.)-499.8(Green)-625(laser)-618.3(\(532)-165.6(nm;)-621(MLB-200A)-623.3(Nd:)-614.8(YAG/KTP)]TJ
1.0828 -1.1116 TD
[(Laser)-245(Treatment)-240.7(Instrument,)-241.5(CHONGQING)-247.4(JINGYU)]TJ
0 -1.1174 TD
[(LASER)-614.4(TECHNOLOGY)-619.9(CO,)-612.3(LTD\))-618.2(and)-609.2(placebo)]TJ
0 -1.1116 TD
[(\(distilled)-340.9(water\))-332.4(were)-335.9(applied)-338.6(in)-336.4(Group)-334.7(A.)]TJ
-1.4169 -1.1116 TD
[(II.)-500.9(NaF)-800(\(Colgate,)-804.9(NY,)-796.5(Duraphat\))-802.3(and)-799.3(green)-802.6(laser)]TJ
1.4169 -1.1174 TD
[(\(532)-165.6(nm\))-338.6(without)-331.5(power)-335.8(were)-335.9(applied)-338.6(in)-336.4(Group)-334.6(B.)]TJ
-1.7509 -1.1116 TD
[(III.)-502(Green)-578.9(laser)-577.9(\(532)-165.6(nm\))-574.7(without)-573.4(power)-577.7(and)-574.7(placebo)]TJ
1.7509 -1.1116 TD
[(\(distilled)-335.1(water\))-338.2(were)-335.9(applied)-338.6(in)-330.6(Group)-334.6(C.)]TJ
-1.7394 -2.229 TD
[(Each)-290.2(patient)-292.7(received)-290(an)-285.6(envelope)-288.9(with)-287.8(a)-290.2(number)-285.4(and)-292.4(the)]TJ
-1.0137 -1.1116 TD
[(numbers)-274.8(were)-278.3(assigned)-275.8(to)-273(one)-269.4(of)-272.9(the)-275.3(three)-272.9(above-mentioned)]TJ
T*
[(groups)-380.8(with)-374.2(unrestricted)-379.7(\(simple\))-379.8(randomization.)-379.9(All)-373.1(treat-)]TJ
0 -1.1174 TD
[(ments)-307.3(were)-307.1(carried)-305(out)-302.9(by)-301.7(an)-302.9(experienced)-306(operator)-305(with)-305(the)]TJ
0 -1.1116 TD
[(same)-439.7(methods)-436.3(and)-436.4(protocols,)-435(and)-436.4(examinations)-438.6(were)-439.6(per-)]TJ
T*
[(forme)-7.8(d)-605.9(b)0(y)-607(another)-609.1(dentist)-608.1(unaware)-611.1(of)-606.9(the)-603.6(grouping)-607.9(to)]TJ
0 -1.1174 TD
[(minimize)-549.6(errors)-548.9(and)-545.9(avoid)-548.2(bias.)-544.6(The)-547.1(patients)-552.7(were)-549(also)]TJ
0 -1.1116 TD
[(blinded)-493(to)-486.1(the)-488.4(therapy)-488.2(received.)-489.3(Each)-491.7(subject)-488.2(received)-491.6(a)]TJ
T*
[(single)-336.1(treatment)-337.5(and)-338.5(was)-333.4(treated)-334(without)-337.3(local)-336.4(anesthesia.)]TJ
1.0137 -1.1174 TD
[(In)-244.1(Group)-248.3(A)-243.9(subjects,)-244.8(the)-246.5(sensitive)-248.4(teeth)-244.2(were)-249.5(irradiated)-245.2(by)]TJ
-1.0137 -1.1116 TD
[(the)-361.7(532-nm)-364.9(green)-359.1(laser)-364.8(at)-360.6(an)-360.5(intensity)-362.7(of)-359.3(15)-163.5(J/cm)]TJ
7.3823 0 0 6.5614 513.6943 236.3527 Tm
(2)Tj
9.843 0 0 9.843 520.8943 231.9873 Tm
(\(param-)Tj
-21.1151 -1.1116 TD
[(eters)-261.2(given)-260.2(in)-255.7(Table)-256.8(1\).)-259(The)-253.3(laser)-261.2(was)-258.6(placed)-257.9(at)-256.9(a)-255.7(distance)-260(of)]TJ
0 -1.1174 TD
[(5)-168.1(m)0(m)-448.2(from)-443.3(the)-448.1(tooth)-449.3(surface)-448.7(and)-442.2(applied)-453.8(on)-439.9(the)-448.1(exposed)]TJ
0 -1.1116 TD
[(denta)-8(l)-508.1(position)-510.1(continually)-510.3(for)-510.1(5)-168.1(min.)-509.2(The)-506.8(adjacent)-514.8(teeth)]TJ
ET
313.058 168.264 239.131 .28348 re
f
313.058 68.542 239.131 .28348 re
f
313.058 139.635 239.131 .28348 re
f
313.058 118.488 239.131 .22678 re
f
313.058 87.364 239.131 .22678 re
f
BT
/F10 1 Tf
9.845 0 0 9.845 340.044 173.9905 Tm
(Table)Tj
/F6 1 Tf
3.0002 0 TD
(1.)Tj
/F10 1 Tf
1.2496 0 TD
[(Parameters)-332.7(of)-337(Light)-335.5(Equipment)]TJ
/F7 1 Tf
-6.9909 -2.8562 TD
[(Wavelength)-2364.2(Mode)]TJ
11.8223 1.0135 TD
[(Fluence)-340(rate)]TJ
.5759 -1.0135 TD
(\(mW/cm)Tj
/F6 1 Tf
7.3837 0 0 6.5625 467.9432 150.2362 Tm
(2)Tj
/F7 1 Tf
9.845 0 0 9.845 471.6282 145.8708 Tm
(\))Tj
2.4531 1.0135 TD
[(Output)-335.3(power)]TJ
1.6988 -1.0135 TD
(\(mW\))Tj
/F6 1 Tf
-20.2586 -1.8946 TD
[(532)-170(nm)-4483.3(CW)-4871.1(47)-5697.2(150)]TJ
/F7 1 Tf
0 -2.4071 TD
[(Tip)-337(diameter)]TJ
0 -1.0135 TD
(\(mm\))Tj
6.4611 1.0135 TD
(Distance)Tj
.7313 -1.0135 TD
(\(mm\))Tj
4.1346 1.0135 TD
[(Treatment)-340.3(time)]TJ
2.0097 -1.0135 TD
[(\(min\))-3720.2(Frequency)]TJ
/F6 1 Tf
-13.3368 -1.8946 TD
[(10)-6992.9(5)-5926.5(5)-6698.2(1)]TJ
8.7511 0 0 8.7511 321.0519 56.7496 Tm
[(CW,)-333.2(continuous)-335.2(wave.)]TJ
/F4 1 Tf
8.9663 0 0 8.9663 62.022 749.6502 Tm
(706)Tj
49.6665 0 TD
[(HU)-334.4(ET)-338.7(AL.)]TJ
ET
endstream
endobj
34 0 obj
<>stream
/GS1 gs
BT
/F6 1 Tf
9.843 0 0 9.843 59.7543 570.8408 Tm
0 0 0 rg
0 Tc
0 Tw
[(were)-347.4(covered)-345.2(with)-339.6(opaque)-343(tinfoil)-342.3(\(Fig.)-341.8(1\).)-339.7(After)-347.4(irradiation)]TJ
0 -1.1116 TD
[(for)-239.4(30)-169.2(min,)-238.5(the)-235(placebo)-241.7(was)-241.3(applied)-240.7(on)-238.3(the)-235(teeth)-244.2(for)-239.4(5)-162.4(min.)-238.5(In)]TJ
0 -1.1174 TD
[(Group)-340.4(B,)-339.6(patients)-339.6(received)-341.9(irradiation)-337.4(of)-342(the)-332.9(532-nm)-341.9(green)]TJ
0 -1.1116 TD
[(laser,)-327.9(but)-326(the)-327.1(power)-324.3(was)-327.7(turned)-324.7(off.)-323.5(After)-324.4(30)-169.2(min,)-324.9(NaF)-322(was)]TJ
T*
[(carefully)-457.1(applied)-448(to)-451.6(the)-448.1(sensitive)-455.7(tooth)-449.3(to)-445.8(ensure)-452.2(that)-449.3(the)]TJ
T*
[(desensitizer)-374.9(made)-370.8(complete)-376.7(contact)-368.6(with)-374.2(the)-367.5(sensitive)-375.1(area)]TJ
0 -1.1174 TD
[(left)-305.3(for)-308.5(5)-168.1(min.)-301.8(Thirty)-307.5(minutes)-303.9(later,)-305.2(the)-309.9(surface)-304.7(of)-307.4(the)-304.1(tested)]TJ
0 -1.1116 TD
[(tooth)-570.2(was)-563.8(dried)-565.5(lightly)-566.9(with)-570(compressed)-568.2(air)-563.3(and)-568.9(rinsed)]TJ
T*
[(thoroughly)-379.9(with)-374.2(water.)-375.1(In)-376.5(Group)-375(C,)-374.2(the)-373.2(operator)-374.1(only)-378.9(pre-)]TJ
0 -1.1174 TD
[(tended)-383.4(to)-370.9(irradi)-8(ate)-374.4(patients)-381(teeth,)-380.1(without)-377.6(laser)-376.4(activation.)]TJ
0 -1.1116 TD
[(Then,)-286.7(a)-278.7(placebo)-282(was)-281.6(applied)-281(according)-284.2(to)-284.6(the)-281.1(same)-278.5(protocol)]TJ
T*
[(with)-362.6(NaF.)-360(All)-361.5(participants)-362.6(were)-364.7(instructed)-364.8(to)-353.7(avoid)-363.9(rinsing)]TJ
0 -1.1174 TD
[(their)-306.4(mouths,)-305(chewing)-304.8(food,)-301.6(or)-301.7(brushing)-302.5(for)-302.7(at)-303(least)-307.4(30)-163.5(min,)]TJ
0 -1.1116 TD
[(3)-168.1(h)0(,)-459.5(and)-453.7(12)-169.2(h,)-453.8(respectivel)-11.2(y,)-453.8(after)-462.9(the)-453.8(treatment.)-461.9(When)-457.1(the)]TJ
T*
[(study)-333.7(was)-333.4(terminated,)-336.3(patients)-333.9(in)-330.6(Group)-334.7(C)-330.4(were)-330.1(recalled)-336.2(to)]TJ
0 -1.1174 TD
[(receive)-340.8(desensitizer)-340.4(application)-338.7(for)-331.5(DH.)]TJ
1.0137 -1.1116 TD
[(During)-261(the)-263.8(study,)-262.3(patients)-259(were)-266.8(required)-258.9(to)-261.5(maintain)-266.2(good)]TJ
-1.0137 -1.1116 TD
[(oral)-403.1(hygiene)-407.6(\(brushing)-401.4(teeth)-405.5(twice)-400.6(a)-405.4(day)-401.9(and)-401.9(using)-402.9(dental)]TJ
T*
[(oss)-435.8(three)-434.1(times)-428.4(a)-434.2(day\))-431.8(and)-430.7(not)-429.7(allowed)-437.4(to)-428.5(use)-436.2(any)-430.7(anti-)]TJ
0 -1.1174 TD
[(hypersensitivity)-302.4(medication)-298.4(or)-290.2(mouthwash.)-298.8(The)-293.6(participants)]TJ
0 -1.1116 TD
[(were)-364.7(followed)-362.4(up)-359.3(at)-360.6(2)-358.2(weeks)-365.6(and)-361.6(3)-358.2(months)-359.1(after)-365(the)-361.7(treat-)]TJ
T*
[(ment.)-430.8(The)-431.9(teeth)-434.3(were)-428(examined)-434.1(with)-431.8(an)-429.6(ice)-432(stick)-427.2(and)-430.7(re-)]TJ
0 -1.1174 TD
[(probing)-572.3(as)-573.4(described)-572(earlier,)-573.5(and)-574.7(the)-569(VAS)-575.1(scores)-573(were)]TJ
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[(obtained.)-291.3(Four)-292.2(scores)-290.7(were)-289.8(recorded)-294.5(for)-285.5(each)-290.1(patient)-292.7(at)-285.7(four)]TJ
T*
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T*
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T*
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[(ance)-284.4(was)-281.6(used)-281.8(to)-278.8(compare)-288.9(the)-281.1(consistency)-280.4(of)-284.4(VAS)-281.4(values)-279.6(at)]TJ
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T*
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T*
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