ࡱ> 574q` RbjbjqPqP2":: '*xxxxxxx  $Qh,  xx xx  xx  x @(- . 0'    xZ@  4F pxxx xxx'  Title:Histological evaluation of different biodegradable and non-biodegradable membranes implanted subcutaneously in rats Author(s): HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=OneClickSearch&field=AU&val=Zhao+SJ&curr_doc=1/1&Form=FullRecordPage&doc=1/1" \o "one-click search" Zhao SJ,  HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=OneClickSearch&field=AU&val=Pinholt+EM&curr_doc=1/1&Form=FullRecordPage&doc=1/1" \o "one-click search" Pinholt EM,  HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=OneClickSearch&field=AU&val=Madsen+JE&curr_doc=1/1&Form=FullRecordPage&doc=1/1" \o "one-click search" Madsen JE,  HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=OneClickSearch&field=AU&val=Donath+K&curr_doc=1/1&Form=FullRecordPage&doc=1/1" \o "one-click search" Donath K Source:JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY 28 (2): 116-122 APR 2000 Document Type:Article Language:English  HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=PagedCitedRefList&UT=000088819600009&doc=1/1&rec_id=116353699" Cited References: 15  HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=DispCitingRec&doc=1/1&isickref=116353699" Times Cited: 7  HYPERLINK "http://wos15.isiknowledge.com/CIW.cgi?SID=Y316aJ2on1aGJIde6pL&Func=EasyRelated&UT=000088819600009&doc=1/1&rec_id=116353699"  INCLUDEPICTURE "http://images.isiknowledge.com/WoK3/Images/relrec.gif" \* MERGEFORMATINET  HYPERLINK ""  INCLUDEPICTURE "http://images.isiknowledge.com/WoK3/Images/info.gif" \* MERGEFORMATINET  Abstract:Different types of biodegradable membranes have become available for guided tissue regeneration. The purpose of this study was to evaluate histologically three different biodegradable membranes (Bio-Gide, Resolut and Vicryl) and one non-biodegradable membrane (expanded polytetrafluoroethylene/e-PTFE) implanted subcutaneously in rats. Five subcutaneous pouches were created in each of 24 rats. One of the four test membranes was randomly placed in each of the four pouches and one pouch was left empty to serve as a control, Histological evaluation was performed after 4, 10 and 21 days which demonstrated that e-PTFE was well tolerated and encapsulated by a fibrous connective tissue capsule. There was capsule formation around Resolut and Vicryl and around Bio-Gide in the early phase there was a wide inflammatory zone already. e-PTFE and Vicryl were stable materials while Resolut and Bio-Gide fragmented in the early phase. In the late phase Vicryl was surrounded by an increasing amount of multinucleated macrophages and a thin capsule, whilst around Resolut and Bio-Gide a strong foreign body reaction was observed. Also granuloma formation was noted around the fragmented Resolut material in its capsule and a mild inflammatory reaction surrounding Bio-Gide within its thin capsule. (C) 2000 European Association for Cranio-Maxillofacial Surgery. KeyWords Plus:GUIDED TISSUE REGENERATION; BONE REGENERATION; RABBIT TIBIA; DEFECTS; OSTEOPROMOTION Addresses:Pinholt EM (reprint author), Vejle Cty Hosp, Dept Oral Maxillofacial Surg, Kabbeltoft 25, Vejle, DK-7100 Denmark Univ Oslo, Natl Hosp, Inst Surg Res, Oslo, Norway Beijing Med Univ, Sch Stomatol, Dept Oral Anat & Physiol, Beijing, Peoples R China Univ Hamburg, Krankenhaus Eppendorf, Inst Oral Pathol, Hamburg, D-2000 Germany Publisher:CHURCHILL LIVINGSTONE, JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND Subject Category:DENTISTRY, ORAL SURGERY & MEDICINE; SURGERY IDS Number:345MK ISSN:1010-5182 z|; < C D F G    жККККiККiККiжКК,h h >*B*CJKHOJQJ^Jph2h h 5>*B*CJKHOJQJ\^Jph6jh h B*CJKHOJQJU^JaJph3h h 5B*CJKHOJQJ\^JaJph-h h B*CJKHOJQJ^JaJph/h h 5B*CJKHOJQJ\^Jph)|  VB $1$a$gd $1$9Da$gd  ) * 6 8 9 ? @ %()*+9:;ϳϳiiM6jh h B*CJKHOJQJU^JaJph-h h B*CJKHOJQJ^JaJph6jh h B*CJKHOJQJU^JaJph-h h B*CJKHOJQJ^JaJph6jh h B*CJKHOJQJU^JaJph,h h >*B*CJKHOJQJ^Jph2h h 5>*B*CJKHOJQJ\^JphV`BS h o(-h h B*CJKHOJQJ^JaJph/h h 5B*CJKHOJQJ\^Jph0182P. 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